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Gretchen Reis

Meet Dr. Gretchen Reis

Gretchen Reis, M.D. is an esteemed physician specializing in bioidentical hormone therapy and the Medical Director of Integrity Wellness Medical Center Charlotte. Dr. Reis is passionate about medicine and her patients, working in partnership with each patient as she helps them discover optimal wellness.

It was her devotion to her patients that led her to leave traditional medicine and join the growing field of functional medicine, where she can address health from a whole body, preventive perspective and uncover the root cause of disease rather than simply managing symptoms. She discovered that correcting underlying issues such as hormone imbalance, poor gut health, and inflammation has a powerful effect in restoring energy, moods and vitality.

Dr. Reis and her husband Bill have 5 children, 4 of whom were adopted out of foster care and one of whom has autism and other developmental disabilities. They have firsthand experience with many parenting challenges but are proud of all of their children, because they have grown into adults and are all doing well. Their youngest with special needs has improved greatly over the years and is a blessing to all who know him.

Medical Career Transformation

Dr. Reis was trained in Family Medicine and started her career in Pennsylvania. She thoroughly loved primary care, so when she and her family moved to Ohio in 2005, she started her own solo practice in a small, underserved community. Her patients loved her compassionate care, but the economic pressure of providing high-quality care in the insurance system became a severe strain. At the same time, she started learning about bioidentical hormones. She completed the Fellowship in Anti-Aging, Functional and Regenerative Medicine. She knew that she now had new tools to help her patients for whom she really hadn’t been able to help much beyond medications to reduce symptoms. She discovered a love for functional medicine and truly getting to the root of symptoms. By bringing in natural healing techniques, she and her patients discovered a new source of joy in health and wellness.

She moved to Charlotte in 2013 to open her new functional medicine practice, specializing in BHRT. Her practice has evolved since then to include more anti-aging techniques, weight loss and environmental-acquired illness. She now uses BHRT, supplements, and support for a healthy lifestyle to help her patients enjoy bountiful health.

Dr. Reis has found that practicing functional medicine makes her a better doctor because she no longer has to focus only on managing symptoms —now, she can “truly get to the root cause of symptoms” and harness a power beyond what traditional medicine can provide.

Today, Dr. Reis takes a preventive approach to medicine, delivering solutions for long term health and the highest quality of life. She began her practice Integrity Wellness Medical Center in Charlotte where she embraces the added time she gets with each patient to address everything that stands between that patient and optimal health.

She has had the honor of being a primary care conference guest speaker on the amazing abilities of bioidentical hormone replacement therapy. Dr. Reis sets an example to her patients by maintaining work-life balance and a healthy lifestyle.

The Team

Crystal Pozo

Crystal Pozo

Office Manager

Crystal is the office manager of Integrity Wellness MD. She has over 14 years in administrative experience in Office Management.  She oversees the daily office operations and makes sure patients have a positive experience and is the first point of contact in your care.  Crystal enjoys meeting new people and is always available to answer your questions and prides herself on providing a high level of customer service.  


Crystal is a married mother of two, who enjoys reading, going to the beach, watching movies, and trying new foods.  Her health, faith, and family are all very important to her. She is always willing to take on a challenge and try new things.  She is currently taking courses in medical management. 

Bill Reis

Bill Reis

Practice Manager

Bill is the manager of the practice, assisting the staff and especially Crystal in business matters. He assists with customer inquiries and helps train the staff in procedures to make the patient experience highly satisfactory. He has a degree from the University of Notre Dame and has worked in business, art and design, and environmental landscaping.


Bill is also a graduate of the Institute of Integrative Nutrition and uses his knowledge and experience in providing health and nutrition coaching to clients. He loves connecting with patients and making sure they get everything they need to achieve the health outcomes they desire. 

Darlene Konopasek

Darlene Konopasek

Lifestyle and Weight Loss Coach

Darlene is the Lifestyle and Weight Loss Coach at Integrity Wellness MD. She works with clients individually assisting them with their nutrition and weight loss goals. She provides meal plans, recipes, education and motivation to clients on our weight loss program. She has completed the Ideal Protein Intensive Coach Training Academy.


Darlene has a Master’s Degree in Education and is also a part-time gifted teacher at her parish school. She uses her teaching skills to counsel and guide patients during their weight loss journey.


Darlene is married and has four children who keep her very active. She enjoys reading, cooking, travelling, and is passionate about teaching and helping others. She has struggled with weight herself and understands the challenges of losing weight and keeping it off.


Darlene has been working as an Ideal Protein coach for over 2 years.

Dr. Reis received her undergraduate degree from the University of Wisconsin and completed her medical degree at Baylor College of Medicine. She completed her residency at Lancaster General Hospital in Lancaster, Pennsylvania, and received the AMA/Glaxo Leadership Award during her time there. Dr. Reis is currently an active member of the American Academy of Anti-Aging Medicine.

Board Certifications, Associations and Training:

  • Member of the American Academy of Anti-Aging Medicine
  • Completed the Fellowship in Anti-Aging, Functional and Regenerative Medicine by the American Academy of Anti-Aging Medicine
  • Board Certified in Family Medicine
  • Board Certified in Integrative Medicine by the American Board of Integrative Medicine (ABOIM)
  • Extensive training in Chronic Inflammatory Response Syndrome
  • Member of the International Society of Environmentally Acquired Illness
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    We reply to all requests promptly, alternatively you can also call us (704) 220-1770 or fax (704) 886-1883.